The natural world seems more complex as we discover more about it. Economic development and explosive population growth in coastal areas add to this complexity. Their direct and indirect impacts are for the most part outside the control of any individual decision-maker and can frustrate traditional management approaches that have been so successful in the past. For example, issues of fisheries overharvest and allocation are complicated by habitat alteration and loss, as well as the deterioration of water quality and loss of freshwater inflows. These are some of the most obvious manifestations. Others may be more subtle, affecting human health or even genetic expression in species. Effective management decisions are becoming increasingly complex as a result, and managers are realizing that their individual success depends upon the decisions and actions of their counterparts. Working together is a daunting but necessary task. One means of helping address this complexity is using a holistic approach that considers interdependencies across components of an entire ecosystem — including humans. At the institutional level, the Harte Model brings interdisciplinary expertise together to provide additional initiatives that offer holistic solutions to Gulf of Mexico problems.